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Search Results for " dot1l in 1 "

4

Compounds

Cat No. Product Name Synonyms Targets
T11081 Dot1L-IN-1 Histone Methyltransferase
The Ki value of DOT1L-in-1 is 2pm.It is a highly effective, selective and novel Dot1L inhibitor.
T73637 Dot1L-IN-1 TFA
Dot1L-IN-1 TFA is a potent and selective Dot1L inhibitor, characterized by a K i of 2 pM and an IC 50 of <0.1 nM. It effectively inhibits H3K79 dimethylation (IC 50 =3 nM) and suppresses the HoxA9 promoter activity (IC 5...
T62915 Dot1L-IN-7
Dot1L-IN-7 (compound 25) is a selective and potent inhibitor of telomere silencing 1-like protein (DOT1L) (IC50: 1.0 μM).Dot1L-IN-7 selectively kills MLL-AF9 and does not affect the growth of E2A-HLF cells.
T63955 MU1656
MU1656, a potent and selective histone methyltransferase DOT1L inhibitor, demonstrates an IC50 of 2 nM. It is applicable in the research of hematological malignancies [1].
TargetMol